Hall missed Saturday's 2-1 defeat at Sheffield Wednesday with a groin injury but is fit to step back in at centre-half against the Seasiders, so Damion Stewart could make way.
Winger Ephraim begins a three-game ban, however, after his late sending-off at Hillsborough for a clash with Franck Songo'o.
Manager Luigi De Canio has an otherwise full squad to choose from and may tinker with his line-up following his side's weekend disappointment.
Midfielder Gavin Mahon got half an hour under his belt as a substitute after missing four games with a knee injury and will be pushing for a start.
Blackpool boss Simon Grayson has no fresh injury concerns as his side look to continue their impressive recent form.
The Seasiders travel to Loftus Road on the back of Saturday's encouraging 2-2 draw with Southampton - their fourth league game unbeaten - with Steve McPhee, Andy Morrell and Paul Dickov all vying for the Seasiders' two attacking berths.
Dickov proved his fitness enough to justify his inclusion in the weekend's starting XI and, despite being substituted in the second half, came through the game unscathed.
Captain Michael Jackson is the only long-term absentee as he remains sidelined with a torn hamstring injury as Grayson's men look to bolster their hopes of a late play-off charge.
Sporting Life