Jose Mourinho's Blues visit Loftus Road looking for a win that will maintain their position as firm favourites to claim the Premier League crown - whilst QPR need the points in their own battle to avoid dropping out of the division all together.
The Rs could start Sunday's derby just one point off the foot of the table despite taking four points from their previous two fixtures.
And, with games running out, Ramsey feels Chelsea's lead at the top means the game takes on extra significance for the hosts.
"It's a big game for us," he said.
"They can afford to have a blip and still win the league but on the flip side, we need to pick up every point we can.
"We all know what it means to the supporters - at this stage of the season, with what is at stake for both teams, it gives it added spice."
Defender Clint Hill, who scored in Tuesday night's 3-3 draw at Aston Villa, enjoyed the taste of victory in his first west London derby when QPR won 1-0 at home to Chelsea in 2011.
That game may now be remembered more for the verbal clash between John Terry and Anton Ferdinand which landed the Chelsea skipper a £220,000 fine and a four-game ban for racial abuse, but Hill wants to see the positives from that performance replicated on Sunday.
"I think we shocked them that day," he told Hoops Player.
"If we can show the same desire both on and off the pitch then hopefully we can get a result again
Nobody expects us to win but we believe we can give them a game.
"We are playing Chelsea who are top of the Premier League and if you can't get up for that challenge then there's something wrong."
Source : PA
Source: PA