The midfielder picked up his fifth booking of the season against Charlton recently and serves a one-match ban.
Leigertwood joins Fitz Hall on the banned list as the centre-half serves the final game of his three-match suspension, but Argentine midfielder Emmanuel Ledesma returns from his ban.
On-loan Bolton striker Heidar Helguson should make his full debut after coming on at half-time during last weekend's draw at Crystal Palace.
Captain Martin Rowlands could also start after coming off the bench at Selhurst Park following a thigh injury, but Lee Cook (knee) and Matthew Connolly (back) are still doubts.
Matteo Alberti (knee) played for the reserves in midweek after 10 weeks out but is unlikely to be considered.
Championship leaders Wolves will be without goalkeeper Carl Ikeme when they travel to face Queens Park Rangers on Saturday.
The stopper has been ruled out as he is still recovering from a bruised hip suffered at Sheffield United last month, meaning Wayne Hennessey will continue in goal.
Fellow goalkeeper Shane Higgs, who arrived on loan from Cheltenham last month, looks set to earn a place on the bench.
Winger Matt Jarvis has recovered from a hamstring injury to put himself back in contention.
But defenders Jody Craddock (broken toe) and George Elokobi (anterior cruciate ligament) remain on the sidelines.
Mick McCarthy was named Championship manager of the month for November, and his side will be looking to continue the good form that has seen them move six points clear at the top of the table.
Sporting Life